5 Ways to Reduce Fatigue and Increase Energy, Naturally

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Are you tired all the time? Fatigue is a message from your body, like a warning light on your dashboard. It’s not just a normal part of aging or overwork. This kind of exhaustion comes from energy depletion — meaning your body can’t create enough energy to keep you going. 

You may try to power through, relying on endless cups of coffee and energy drinks. These provide a quick boost, but they eventually lead to an energy crash later on. That’s because stimulants like caffeine deal with the surface problem, not the root causes of low energy. And it’s why powering through just makes you feel worse — until you eventually burn out completely. 

8 Symptoms of Fatigue

When true fatigue hits, you’ll feel it through your whole body. That’s because fatigue is more than being tired. It involves a breakdown in your body’s energy production — and that affects every cell and system in your body.  

Here are 8 symptoms of fatigue symptoms — other than feeling tired and weary – that you may be struggling with: 

  • Depression 
  • Irritability 
  • Brain fog and mental exhaustion 
  • Headaches 
  • Achy muscles and joints 
  • Sugar cravings 
  • Unintended weight changes 
  • Frequent colds and other infections 

Fatigue takes quite a toll on you. But you can overcome fatigue, and get your vitality back by restoring your body’s ability to create plenty of energy.

How Your Body Creates Energy

Your energy starts at the cellular level.  

All of the cells in your body contain their own miniature “power plants” called mitochondria.1 And the number of mitochondria in any particular cell depends on what that cell does and how much energy it needs. For example, muscle cells have many more mitochondria than skin cells – not surprising when you think about how much your muscles move every day. 

Your mitochondria take raw materials — glucose and oxygen — and convert them into energy. That energy gets stored in special molecules called ATP.2 When a cell needs to use energy, the ATP releases it. Think of it like withdrawing money from a savings account. 

To keep you going, your mitochondria need a steady supply of oxygen, glucose, and nutrients – including zinc and B vitamins – that support energy creation. That’s why respiration and circulation play such important roles in your energy levels — every breath you take (respiration) supplies fresh oxygen. And your blood (circulation) delivers all of the necessary energy ingredients to your mitochondria.  

But when there’s even a small glitch anywhere in this system, it can rob you of vitality and motivation, leaving you feeling sluggish, weak, tired, and sick. 

Everyday Stress Steals Your Vitality

Stress is exhausting for your body, mind, and spirit. There’s a reason that stress feels so draining – it depletes your energy and decreases your body’s ability to create energy. And while you might think stress comes from things like simultaneously managing work and kids or paying bills, it involves so much more. 

5 Energy Drains

  1. Toxin exposure3  
  2. Systemic inflammation4 
  3. Oxidative stress5 
  4. Immune system reactions6 
  5. Mitochondrial dysfunction7

You might not even realize you’re dealing with these energy thieves – but that doesn’t stop them from leaving you exhausted all the time. And, all too often, several of them can show up at once.

When Fatigue Signals Something More

Sometimes, fatigue involves more than your body’s temporary reactions to stressors. Frequent or long-term fatigue may also signal a more serious underlying condition. Unfortunately, fatigue-related conditions often get overlooked or dismissed, partly because they’re tough to accurately diagnose. 

But if your fatigue has been dragging on for at least six months, and even minor exertion wipes you out, you may be dealing with one of these heavy-hitters: 

  • Chronic fatigue syndrome (CFS), a debilitating condition that brings on extreme tiredness along with a wide range of other symptoms.8 
  • Post-viral syndrome, which (like it sounds) appears after a significant viral infection (such as Covid Long Haul) and causes long-term symptoms including extreme fatigue9,10 
  • Adrenal fatigue, a condition (not yet recognized by many mainstream medical professionals) where overworked, overstressed adrenal glands can’t produce the hormones needed to keep you feeling energized and calm 

Whether you’re dealing with long-term fatigue or one of these more severe diagnoses, you might feel hopeless, like there’s nothing you can do to get your energy and your life back — but you can!

5 Natural Ways to Boost Energy and Vitality

To overcome chronic fatigue and restore natural energy and vitality, you need a multi-system approach. After all, this isn’t a simple, single-target problem. So you need the right combination of strategies for an effective solution. 

This five-target plan addresses all of the factors that can sap your energy. And when you approach your fatigue from every angle, you have a much better chance for lasting success.

1. Target Toxins

You’re exposed to energy-stealing toxins every day lurking inside everything from household cleaning products to polluted air to moldy basements. And even low-level exposure takes a toll when it happens every day for years. That toxin build-up takes a toll on all of  your body systems, making you feel tired and rundown all the time.  You can help your body gently detox at a safe pace with Modified Citrus Pectin (MCP).11 Clinical studies show that MCP helps your body safely neutralize and eliminate toxins, including heavy metals like lead and mercury, radioactive particles, and environmental chemicals.12,13

2. Reduce Inflammation

Systemic, chronic inflammation lies at the root of every disease state you can think of, and that includes your struggle with fatigue. You can help your body get runaway inflammation under control and promote a healthy inflammatory response with proven botanicals including: 

3. Manage Stress 

You’re faced with stress all the time, and that can drain your body’s deepest reserves and overtax your adrenal system. When your adrenals are always “on call,” your body never gets a chance to calm down and relax. That’s where balancing formulas like MycoAdrenal make all the difference. MycoAdrenal contains 5 powerful, botanically-enhanced medicinal mushrooms, all proven to provide substantial adrenal support and fatigue relief:18 

  • Cordyceps19 
  • Reishi20 
  • Maitake21 
  • Turkey tail22
  • Shiitake23,24 

Along with their stress-balancing activity, these prized mushrooms act like a mild energy tonic to help overcome deep fatigue. Another beneficial “side effect” of the MycoAdrenal mushroom team: They help balance your immune response, another important factor in energy production and fatigue relief. 

4.  Improve Circulation

Your energy levels depend on your circulation, your body’s delivery system. Without healthy circulation, oxygen and nutrients can’t get where they need to go. That can leave your cells starving for energy — and leave you feeling exhausted all the time. The best natural options for improving circulation include: 

  • Salvia miltiorrhiza25 
  • Nattokinase26 
  • Hawthorn27 
  • Ginkgo28 

5. Boost Mitochondrial Function

Your mitochondria have one of the most important jobs in your body – producing energy – and they need a lot of support to keep up with the demands. When they’re not working at peak capacity, you’ll feel the exhaustion in every cell of your body. Support your mitochondria and increase cellular energy with targeted nutrients and botanicals including: 

  • Essential energy nutrients, like B vitamins, zinc, and selenium 
  • Acetyl-L-carnitine (an amino acid)29,30
  • Astragalus31 
  • Siberian ginseng32 

This 5-target holistic approach offers a long-lasting solution for crushing fatigue — a solution that will sustain you with fresh energy every day.  


[1] Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. The Mitochondrion. Available from: https://www.ncbi.nlm.nih.gov/books/NBK26894/ 

[2] Bertram R, Gram Pedersen M, Luciani DS, Sherman A. A simplified model for mitochondrial ATP production. J Theor Biol. 2006 Dec 21;243(4):575-86. doi: 10.1016/j.jtbi.2006.07.019. Epub 2006 Jul 25. PMID: 16945388. 

[3] Racciatti D, Vecchiet J, Ceccomancini A, Ricci F, Pizzigallo E. Chronic fatigue syndrome following a toxic exposure. Sci Total Environ. 2001 Apr 10;270(1-3):27-31. doi: 10.1016/s0048-9697(00)00777-4. PMID: 11327394. 

[4] Lacourt TE, Vichaya EG, Chiu GS, Dantzer R, Heijnen CJ. The High Costs of Low-Grade Inflammation: Persistent Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-adaptive Energy Expenditure. Front Behav Neurosci. 2018;12:78. Published 2018 Apr 26. doi:10.3389/fnbeh.2018.00078 

[5] Lee JS, Kim HG, Lee DS, Son CG. Oxidative Stress is a Convincing Contributor to Idiopathic Chronic Fatigue. Sci Rep. 2018;8(1):12890. Published 2018 Aug 27. doi:10.1038/s41598-018-31270-3 

[6] Lorusso L, Mikhaylova SV, Capelli E, Ferrari D, Ngonga GK, Ricevuti G. Immunological aspects of chronic fatigue syndrome. Autoimmun Rev. 2009 Feb;8(4):287-91. doi: 10.1016/j.autrev.2008.08.003. Epub 2008 Sep 16. PMID: 18801465. 

[7] Filler K, Lyon D, Bennett J, McCain N, Elswick R, Lukkahatai N, Saligan LN. Association of Mitochondrial Dysfunction and Fatigue: A Review of the Literature. BBA Clin. 2014 Jun 1;1:12-23. doi: 10.1016/j.bbacli.2014.04.001. PMID: 25147756; PMCID: PMC4136529. 

[8] Bjørklund G, Dadar M, Pivina L, Doşa MD, Semenova Y, Maes M. Environmental, Neuro-immune, and Neuro-oxidative Stress Interactions in Chronic Fatigue Syndrome. Mol Neurobiol. 2020 Nov;57(11):4598-4607. doi: 10.1007/s12035-020-01939-w. Epub 2020 Aug 6. PMID: 32761353. 

[9] Wostyn P. COVID-19 and chronic fatigue syndrome: Is the worst yet to come? Med Hypotheses. 2021 Jan;146:110469. doi: 10.1016/j.mehy.2020.110469. Epub 2021 Jan 2. PMID: 33401106; PMCID: PMC7836544. 

[10] Perrin R, Riste L, Hann M, Walther A, Mukherjee A, Heald A. Into the looking glass: Post-viral syndrome post COVID-19. Med Hypotheses. 2020;144:110055. doi:10.1016/j.mehy.2020.110055 

[11] Eliaz I, Raz A. Pleiotropic Effects of Modified Citrus Pectin. Nutrients. 2019 Nov 1;11(11):2619. doi: 10.3390/nu11112619. PMID: 31683865; PMCID: PMC6893732. 

[12] Eliaz I, Weil E, Wilk B. Integrative medicine and the role of modified citrus pectin/alginates in heavy metal chelation and detoxification–five case reports. Forsch Komplementmed. 2007 Dec;14(6):358-64. doi: 10.1159/000109829. Epub 2007 Dec 12. PMID: 18219211. 

[13] Eliaz I, Weil E, Schwarzbach J, Wilk B. Modified Citrus Pectin / Alginate Dietary Supplement Increased Fecal Excretion of Uranium: A Family. Altern Ther Health Med. 2019 Jul;25(4):20-24. PMID: 31202207. 

[14] Gupta A, Vij G, Sharma S, Tirkey N, Rishi P, Chopra K. Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model. Immunobiology. 2009;214(1):33-9. doi: 10.1016/j.imbio.2008.04.003. Epub 2008 Jun 17. PMID: 19159825. 

[15] Shimizu K, Funamoto M, Sunagawa Y, et al. Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases. Eur Cardiol. 2019;14(2):117-122. Published 2019 Jul 11. doi:10.15420/ecr.2019.17.2 

[16] Khalid S, Ullah MZ, Khan AU, et al. Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling. Front Pharmacol. 2018;9:140. Published 2018 Mar 20. doi:10.3389/fphar.2018.00140 

[17] Javed S, Mitchell K, Sidsworth D, Sellers SL, Reutens-Hernandez J, Massicotte HB, Egger KN, Lee CH, Payne GW. Inonotus obliquus attenuates histamine-induced microvascular inflammation. PLoS One. 2019 Aug 22;14(8):e0220776. doi: 10.1371/journal.pone.0220776. PMID: 31437163; PMCID: PMC6706056. 

[18] Geng P, Siu KC, Wang Z, Wu JY. Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms. Biomed Res Int. 2017;2017:9648496. doi:10.1155/2017/9648496 

[19] Lin B, Li S. Cordyceps as an Herbal Drug. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 5. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92758/ 

[20] Rossi P, Buonocore D, Altobelli E, et al. Improving Training Condition Assessment in Endurance Cyclists: Effects of Ganoderma lucidum and Ophiocordyceps sinensis Dietary Supplementation. Evid Based Complement Alternat Med. 2014;2014:979613. doi:10.1155/2014/979613 

[21] Vetvicka V, Vetvickova J. Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts. Ann Transl Med. 2014;2(2):14. doi:10.3978/j.issn.2305-5839.2014.01.05 

[22] Benson KF, Stamets P, Davis R, et al. The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro. BMC Complement Altern Med. 2019;19(1):342. Published 2019 Dec 2. doi:10.1186/s12906-019-2681-7 

[23] Dai X, Stanilka JM, Rowe CA, Esteves EA, Nieves C Jr, Spaiser SJ, Christman MC, Langkamp-Henken B, Percival SS. Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults. J Am Coll Nutr. 2015;34(6):478-87. doi: 10.1080/07315724.2014.950391. Epub 2015 Apr 11. PMID: 25866155. 

[24] Zembron-Lacny A, Gajewski M, Naczk M, Siatkowski I. Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise. J Physiol Pharmacol. 2013 Apr;64(2):249-54. PMID: 23756400. 

[25] Wang L, Ma R, Liu C, et al. Salvia miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases. Curr Pharm Des. 2017;23(7):1077-1097. doi:10.2174/1381612822666161010105242 

[26] Chen H, McGowan EM, Ren N, et al. Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomark Insights. 2018;13:1177271918785130. Published 2018 Jul 5. doi:10.1177/1177271918785130 

[27] Wu M, Liu L, Xing Y, Yang S, Li H, Cao Y. Roles and Mechanisms of Hawthorn and Its Extracts on Atherosclerosis: A Review. Front Pharmacol. 2020;11:118. Published 2020 Feb 21. doi:10.3389/fphar.2020.00118 

[28] Wu Y, Li S, Cui W, Zu X, Du J, Wang F. Ginkgo biloba extract improves coronary blood flow in healthy elderly adults: role of endothelium-dependent vasodilation. Phytomedicine. 2008 Mar;15(3):164-9. doi: 10.1016/j.phymed.2007.12.002. Epub 2008 Feb 6. PMID: 18258419. 

[29] Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, Calvani R, Cantatore P, Gadaleta MN, Pesce V. Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. Exp Gerontol. 2017 Nov;98:99-109. doi: 10.1016/j.exger.2017.08.017. Epub 2017 Aug 12. PMID: 28807823. 

[30] Pagano G, Pallardó FV, Lyakhovich A, et al. Aging-Related Disorders and Mitochondrial Dysfunction: A Critical Review for Prospect Mitoprotective Strategies Based on Mitochondrial Nutrient Mixtures. Int J Mol Sci. 2020;21(19):7060. Published 2020 Sep 25. doi:10.3390/ijms21197060 

[31] Li XT, Zhang YK, Kuang HX, et al. Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism. Int J Mol Sci. 2012;13(2):1747-1761. doi:10.3390/ijms13021747 

[32] Sumiyoshi M, Kimura Y. Effects of Eleutherococcus senticosus Cortex on Recovery from the Forced Swimming Test and Fatty Acid β-Oxidation in the Liver and Skeletal Muscle of mice. Nat Prod J. 2016 Mar;6(1):49-55. doi: 10.2174/2210315506999151207145020. PMID: 28553575; PMCID: PMC5427804. 

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